Protesters, seen waving Palestinian flags, interrupted the 70-year-old’s show at the ICC Sydney Theatre last night, calling him a “hack” and a “fraud”.
“It doesn’t affect me,” Seinfeld told them.
“All these people, you’re ruining their night.”
The protesters were escorted from the venue by security.
It’s the second time Seinfeld has been interrupted by hecklers during his Australian tour.
“We have a genius, ladies and gentlemen,” Seinfeld said in response.
“He solved the Middle East.
“It’s the Jewish comedians, that’s who we have to get.
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“They’re the ones doing everything.”
The US comedian’s next show will be at Brisbane tonight.
He then plays stages in Adelaide and Melbourne before his tour wraps up.