By Melody Fletcher and Eirian Jane Prosser
10:24 28 Jun 2024, updated 12:12 28 Jun 2024
An unnamed A-list celebrity hooked on the weight loss Ozempic was forced to flee Gwyneth Paltrow‘s holiday home in The Hamptons after apparently losing control of their bowls.
Word of the mortifying incident is said to have quickly spread through the elite American beach town with many pondering who the celebrity guest could be.
Unable to face the consequences of the Ozempic-induced diarrhoea, the star reportedly snuck of Paltrow’s sprawling home and headed back to New York City to hide in shame.
The medication, typically used to treat diabetes, has quickly become known as Hollywood’s ‘worst kept slimming secret’, allowing people to shed weight quickly.
Yet while the benefits of the jab have spread like wildfire in California and beyond, many have failed to relay the the common side-effect that affects one in 10 users of the drug.
The active ingredient of semaglutide not only triggers weight loss but causes gastrocolic reflex, which can lead to explosive and uncontrollable diarrhoea.
The embarrassing ‘scandal’ was first reported in a weekly gossip magazine as a blind item.
It read: ‘Ozempic-induced diarrohea is becoming a very hot topic of conversation between hosts there — because so many of their guests are using it,’ the recent blind item claimed. So expect laundrettes to be fully booked from July 4.’
There are no suggestions that Paltrow herself had ever used or was using Ozempic or similar medication, only that a guest at her house might have experienced the unpleasant side-effects of the drug.
MailOnline is also not suggesting that an celebrity named or pictured in this story is suffering or has ever suffered from the gastrointestinal side effect described in the Popbitch newsletter.
In recent months, a handful of celebrities have admitted to using the Ozempic, including Oprah Winfrey, Elon Musk, Sharon Osbourne, Chelsea Handler and Robbie Williams.
Amongst them is comedian Am Schumer, who admitted taking the drug in 2022 but announced in June 2023 she had quit due to side effects. ‘I was one of those people who felt so sick,’ she said.
Weight loss drugs work by mimicking GLP-1, a hormone made naturally in the body that helps slow the passage of food through the stomach, in turn making people feel less hungry.
It also alters the brain’s appetite regulation so that users feel satiated despite eating less and they also don’t experience cravings for treat foods.
Clinical trials show that 30 per cent of patients experience diarrohea on Wegovy, compared to 16 percent on the placebo, according to the drug’s prescribing information.
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Common side effects of Ozempic include constipation, diarrhea, nausea, vomiting, and abdominal pain, according to the drug’s label.
Meanwhile, longer-term side-effects have also started to emerge.
Muscle loss is one key side effect after scientists looking into the GLP-1 drugs showed roughly 40 per cent of weight loss is muscle mass rather than fat.
This can have serious long term health impacts as not only are muscles needed to burn calories but for those who are middle-aged or elderly, muscle loss can lead to fragility or even early death.
Less common complications of GLP-1 medications are gallstones, increased heart rate, kidney damage and pancreatitis — a condition where the pancreas rapidly becomes painfully inflamed.
Another serious concern is gastroparesis, a severe disorder where the stomach muscles become effectively paralysed and the stomach does not empty, and sufferers vomit days-old food.
For some patients, the only remedy for gastroparesis may be a gastric bypass.