Elsewhere on Wednesday, Daniil Medvedev fought back from a set and a break down to defeat Frenchman Alexandre Muller.
The Russian fifth seed won 6-7 7-6 (7-4) 6-4 7-5 after three hours and 28 minutes on Centre Court.
“It was never easy but I managed to stay solid, stay in the match, try to fight back,” said 28-year-old Medvedev.
“I’m definitely happy with the win – I should have played much better but when you win, there is the next round to do better.”
Medvedev, who reached the semi-finals at Wimbledon last year, will face Germany’s Jan-Lennard Struff in the third round.
Eighth seed Casper Ruud fell to a 6-4 7-5 6-7 (1-7) 6-3 defeat by world number 94 Fabio Fognini of Italy.
It is the third year in a row that Norway’s Ruud, who prefers clay and hard-court surfaces to grass, has lost in the second round at Wimbledon.
Frenchman Gael Monfils is two games away from the third round after he took a 7-6 (7-5) 6-4 5-5 lead over three-time Grand Slam winner Stan Wawrinka before play was suspended because of fading light.
American 12th seed Tommy Paul was taken the distance by world number 147 Otto Virtanen before the Queen’s champion claimed a 4-6 6-3 5-7 7-5 6-4 win on court three.
Meanwhile, Thanasi Kokkinakis of Australia saved four match points on his way to a 4-6 5-7 7-6 (11-9) 6-4 6-4 victory against 17th seed Felix Auger-Aliassime.